Top 5 most anticipated 49ers games of the 2022 season

Stephen R. Sylvania – USA TODAY Sports

After posting a 10-7 record and winning a playoff game in the 2021 season, expectations for the San Francisco 49ers for this upcoming season have only grown. The 49ers’ opponents for next season have already been revealed and they have the fifth-toughest schedule this season when looking at combined 2021 team winning percentage (.533).

With the schedule looking pretty tough this season, there should be a plethora of epic 49ers games this season. In turn, let’s take a look at the five games 49ers fans should have circled on their schedule this season.

5. 49ers vs. Tampa Bay Buccaneers

Tom Brady will enter Levi Stadium for the first time since 2016 in Week 11 with the New England Patriots. Brady and the 49ers had a lot of drama between them after numerous trade rumors, both before and after Brady’s trade. Nonetheless, the Tampa Bay Buccaneers should be a contending team in the NFC, returning most of their most important plays.

This game will be a pivotal home game for the 49ers, who will face some of their toughest home opponents including the Chiefs, Chargers, Rams and Dolphins this season. The 49ers haven’t faced the Bucs since kicking off the 2019 season when Jameis Winston threw three interceptions for the 49ers. Obviously, this Bucs team is a totally different machine, bringing Brady back with Godwin and Evans in the mix will always be a problem for secondaries across the league.

Speaking of secondaries, this game will give the 49ers a chance to show off newly acquired cornerback Charvarius Ward and the rest of the secondary. A glaring weakness of the 2021 season has been the niners pass defense and that will be something to watch in this game, along with the Bucs’ elite passing offense.

4. 49ers vs. Los Angeles Rams

The defending Super Bowl champions will come to town for their annual meeting with the 49ers at Levi Stadium. After a 20-17 loss in the NFC Championship, this home game will be huge for San Francisco and their season.

The Rams will look a little different this season after leaving longtime receiver Robert Woods and adding Allen Robinson. Most parts come back with Matthew Stafford and Cooper Kupp coming off of an incredible season.

Last season, the 49ers went 2-0 against Los Angeles in the regular season before falling in the NFC Championship Game. The two games against the Rams will be crucial, but securing that home win would be a big boost for the 49ers and their season.

3. 49ers @ Las Vegas Raiders

The 49ers will play all of AFC West this season, which is arguably the most competitive and well-rounded division in football.

Vegas may have the most explosive offense on paper, with Darren Waller, Davante Adams, Hunter Renfrow and Josh Jacobs. With a capable quarterback like Derek Carr, the Raiders will likely fight for a playoff spot.

Where the Raiders have question marks is up front on the offensive line. According to PFF, the Raiders had the 28th-best offensive line in the NFL last season. Although they made a few offseason acquisitions, the 49ers should be able to exploit them there.

San Francisco is the much better team in the trenches and winning this one on the road would be a bold move for the rest of the season. In what will likely be a prime-time game, the 49ers should shine on the national stage against a less physical opponent.

2. 49ers @ Denver Broncos

Russell Wilson and San Francisco will meet again, this time with their new team at Mile High Stadium. A reloaded formation after this offseason, the Broncos will be one of the most formidable opponents on the calendar this year.

The creme de la creme seems to be in the AFC this season, with most of the roster movement happening there. It’s going to be a huge game for the 49ers no matter where it is on the schedule.

Most of the 49ers’ road games this season are against weaker opponents. This game gives the 49ers the opportunity to eliminate probably the toughest road opponent they have on the schedule this year.

1. 49ers vs. Chiefs

AFC West’s third game in a row, but arguably the most anticipated game of the entire calendar. The last time the 49ers saw Patrick Mahomes and the Chiefs was at Super Bowl LIV where the niners went down 20-17.

It should be an electric atmosphere at Levi’s Stadium as the niners seek revenge for the first time since the loss. The Chiefs will now be without Tyree Hill, having traded him to the Miami Dolphins this offseason, which should help the 49ers.

Nonetheless, Andy Reid and the Kansas City Chiefs are the AFC’s top dogs until proven otherwise.

The San Francisco 49ers face two-time defending Super Bowl champions, the Los Angeles Rams. They also face the Raiders for the first time since the latter left the Bay Area for Las Vegas. The two formerly local rivals will play at the Allegiant Stadium. The 49ers are also home to briefly retired Tom Brady and the Tampa Bay Buccaneers. Every time the Niners take on Brady, fans are treated (told sarcastically) to stories of how the future Hall of Fame quarterback loved the Bay Area team growing up and dreamed of playing for the 49ers. He has won seven Super Bowls since. Or, more recently, how the Niners managed to sign Brady in 2020. The quarterback won that seventh Super Bowl that season. None of these confrontations is

The San Francisco 49ers made former UCF defensive tackle Kalia Davis a sixth-round pick. He might not be available for the start of the 2022 season, however. Davis suffered a torn ACL in October, likely dropping his draft stock and allowing San Francisco to select him with the No. 220 pick overall. The 49ers are hoping Davis can replace another defensive tackle who left in free agency. “Kalia Davis, he’s a guy you see a lot of DJ Jones in,” general manager John Lynch said after the draft concluded on Saturday. “That type of explosion. Had an ACL injury. We’re going to take our time to make sure Kalia is right, so I don’t know if he’ll be ready for the start of the regular season. “He could be a PUP guys, but [we] really just love [him]. It matches exactly

The San Francisco 49ers should be pretty good in 2022, right? Yes, they enter the upcoming season with a sophomore starting quarterback who only played 178 snaps last season, and the inside of the offensive line is uncertain, but the rest of the core remains. San Francisco has been in the playoffs in two of the last three seasons, with an injury-plagued 2020 campaign being the exception. There’s always star power with names like George Kittle, Trent Williams, Nick Bosa, Fred Warner and hopefully Deebo Samuel. Winning the NFC West against the defending Super Bowl champion Los Angeles Rams can be an uphill battle, but they’ll surely make the playoffs, won’t they? CBS Sports’ Jason La Canfora doesn’t believe it. He

With the first round of the 2022 NFL Draft now in the books, the picture is starting to become a bit clearer on who the 49ers can select with their second-round pick. The 49ers hold the 61st pick in the second round of the draft and the position they resume for is unknown, but this draft class appears to be deep in the right positions for San Francisco. Many fictional drafts have the 49ers pick a defensive back or possibly an EDGE, but either way, the 49ers will have plenty of solid players to choose from. S Jalen Pitre (Baylor): It’s unlikely Pitre will still be there this deep in the second round, but if he slides to the 49ers, they should pounce. Pitre would bring versatility the 49ers secondary desperately needs, with Charvarius Ward now on the outside with

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